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Syphilis Testing Options

Fast, Confidential Syphilis Testing

Test for syphilis with the Rapid Plasma Reagin Test with confirmation, as expertly selected by our Medical Advisory Board. This highly sensitive, FDA-approved syphilis test screens for antibodies in the blood for a quick and private testing experience.

The Syphilis Test Process

Syphilis Test Details

Syphilis testing is fast, accurate and fully confidential. This type of test is the most advanced on the market with accuracy rates over 99%. This syphilis test uses a small blood sample, which is provided at a local lab of your choice. Since screening is performed via blood, there are no uncomfortable exams, undressing or swabbing.

Where to Test for Syphilis

Syphilis testing is offered nationwide at nearly 4,000 local testing centers. These are the same FDA-approved labs used and trusted by doctors and hospitals everywhere. All labs are private and offer a wide range of diagnostic testing—not just STD testing—so no one will know why you are there. Appointments are never required and testing takes 15 to 20 minutes at the lab.

Viewing Your Results understands STD testing is a private matter, so we are dedicated to providing answers quickly. Syphilis results are ready 1 to 5 business days after testing and are accessible in our secure, online portal or by phone.

Things to Know Before Your Syphilis Test

When to get a Syphilis Test

The syphilis window period—the time between possible exposure and when the syphilis test can accurately detect antibodies—is 3 to 6 weeks. When screening as a general checkup, syphilis testing is advised for all sexually active adults.

Common Syphilis Symptoms

Like all STDs, syphilis can occur without noticeable symptoms. When symptoms are present, they can be vague which makes them difficult to diagnose without a syphilis test. The first sign of syphilis is often a single, painless sore or “chancre” around the genitals. This chancre can heal without treatment, but the syphilis infection is still present in the body. As the infection progresses, individuals may experience a rough, reddish rash on the hands and feet, which can also heal without treatment. 1

Why Screen for Syphilis

Syphilis, once a rare STD, has become more prevalent in recent years. Routine syphilis testing is important, because this STD is better cured when diagnosed early. Left untreated, syphilis can cause brain, organ and bone damage. Also, if syphilis sores are present, a person is 2 to 5 times more likely to contract HIV if exposed.2

Positive? We’ll Help You With Syphilis Treatment. does more than just testing. If positive, trained counselors are available to help interpret your results. Staff physicians are also available for a free, one-on-one phone consultation to go over positive syphilis test results and provide medical advice. Syphilis is curable with a shot of antibiotics, and our doctors can help you find treatment in your area.

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Additional Syphilis Resources



  1. American Sexual Health Association. Syphilis. American Sexual Health Association. Accessed April 2013.
  2. Centers for Disease Control and Prevention. Syphilis – CDC Fact Sheet. Centers for Disease Control and Prevention. Accessed April 2013.  

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Complete STD Tests Package

  • Chlamydia
  • Gonorrhea
  • HIV Standard
  • Syphilis
  • Oral Herpes
  • Genital Herpes
  • Hepatitis B
  • Hepatitis C
Fastest Results!

The HIV early detection test is a DNA-based test that can detect the virus as early as two weeks after possible exposure. However, our physician's recommend pairing the early detection test with the HIV Standard test, which is considered the "gold standard" in HIV screening. However, it may take up to 12 weeks for the HIV Standard test to provide accurate results. Repeat HIV testing is recommended for sexually active adults with multiple partners or concern of exposure.