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What's the difference between HPV and HSV...are they related in any way?
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Nope, no direct connection between the two, although there are similarities. HPV is the Human Papillomavirus, which can cause warts most anywhere on the body. Some types of HPV (there are more than 100 altogether) prefer genital/anal skin and can cause genital warts ("low risk' HPV). Some other types of HPV, called "high risk" types, can cause abnormal cell changes to a woman's cervix which, if undetected, can sometimes lead to cancer. Even these types of HPV are rarely dangerous, but it's a good idea for women to have regular Pap tests as a precaution.
HSV is of course the Herpes Simplex Virus. HSV-1 is usually associated with cold sores, while HSV-2 is most often found with genital herpes (in truth, though, either type can infect oral/genital tissue).
HPV and HSV are transmitted the same way, skin to skin contact rather than fluid exchange. In this discussion, that means anal and vaginal sex, and any genital-to-genital contact, even without penetration.
Hope that helps.